Lentivirus production refers to the process of generating lentiviral particles for research or therapeutic applications. This involves co-transfection of plasmids (packaging, envelope, and transfer plasmids) into a host cell line (usually HEK293T cells) to produce the viral particles. The process includes transfection, harvesting of viral supernatants, and purification to obtain high-titer, functional lentivirus. Lentivirus production is a critical step in applications such as stable gene expression, gene knockdown using shRNA, and preclinical gene therapy studies.
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custom aav
Custom AAV refers to tailor-made AAV vectors designed to meet specific research or therapeutic needs. These vectors can be engineered to carry unique genetic payloads, target specific cell types, or utilize a desired serotype for optimal delivery. Customization options include promoter selection, cargo optimization, and capsid modifications to ensure precise functionality. Custom AAV services cater to diverse applications such as gene therapy, disease modeling, and functional genomics studies.
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