Effect of high-dose aldehyde dehydrogenase 2 on xenobiotic detoxification in porcine cardiac myocytes.
The present study was designed to clarify the functional consequence of aldehyde dehydrogenase 2 (ALDH2), which is responsible for the oxidation of acetaldehyde to acetic acid in tissues, on xenobiotic metabolism. This study was performed in the pig heart which is considerably susceptible to acetaldehyde-induced cardiotoxicity because ALDH2 is low in 66cf4387b8 iphisib
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